T 2 *-based fiber orientation mapping

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T2*-based fiber orientation mapping

Recent MRI studies at high field have observed that, in certain white matter fiber bundles, the signal in T(2)*-weighted MRI (i.e. MRI sensitized to apparent transverse relaxivity) is dependent on fiber orientation θ relative to B(0). In this study, the characteristics of this dependency are quantitatively investigated at 7 T using ex-vivo brain specimens, which allowed a large range of rotatio...

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White matter fiber orientation mapping based on T2* anisotropy

Introduction Recent studies have shown that T2 relaxation may be anisotropic [1-4]. This anisotropy has been attributed to the microscopic (sub-voxel level) anisotropic distribution of susceptibility perturbers. In white matter fiber bundles, these anisotropic pertubations could originate from compounds such as lipid and ferritin that may align with axons, and could generate magnetic field vari...

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Magnetic resonance myocardial fiber-orientation mapping with direct histological correlation.

Functional properties of the myocardium are mediated by the tissue structure. Consequently, proper physiological studies and modeling necessitate a precise knowledge of the fiber orientation. Magnetic resonance (MR) diffusion tensor imaging techniques have been used as a nondestructive means to characterize tissue fiber structure; however, the descriptions so far have been mostly qualitative. T...

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Myocardial fiber orientation mapping using reduced encoding diffusion tensor imaging.

A precise knowledge of the myocardial fiber architecture is essential to accurately understand and interpret cardiac electrical and mechanical functions. Diffusion tensor imaging has been used to noninvasively and quantitatively characterize myocardial fiber orientations. However, because the approach necessitates diffusion to be measured in multiple encoding directions and frequently at multip...

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Quantitative mapping of scleral fiber orientation in normal rat eyes.

PURPOSE Previous work has suggested a major role of scleral biomechanics in the pathogenesis of glaucoma. Since fiber orientation in connective tissues is a key determinant of tissue biomechanics, experimental characterization of scleral fiber orientation is needed to fully understand scleral biomechanics. This is a report of baseline experimental measurements of fiber orientation in whole norm...

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ژورنال

عنوان ژورنال: NeuroImage

سال: 2011

ISSN: 1053-8119

DOI: 10.1016/j.neuroimage.2011.04.026